STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phoUPhosphate transport system regulatory protein phou; Plays a role in the regulation of phosphate uptake (234 aa)    
Predicted Functional Partners:
pstB
Phosphate transport system atp-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
 
  
 0.995
pstA
3a0107s02c: phosphate ABC transporter, permease protein PstA
 
  
 0.994
phoB
Two-component system, ompr family, phosphate regulon response regulator phob; Two-component system response regulator; phoB: phosphate regulon transcriptional regulatory protein PhoB
  
 0.989
phoR
Two-component system, ompr family, phosphate regulon sensor histidine kinase phor; PAS domain-containing sensor histidine kinase; phoR_proteo: phosphate regulon sensor kinase PhoR
 
 
 0.983
pstC
Phosphate abc transporter, permease protein pstc; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane
 
  
 0.976
pstS
Phosphate abc transporter, phosphate-binding protein psts; Part of the ABC transporter complex PstSACB involved in phosphate import
 
 
 0.969
ppx
annotation not available
     
 0.782
ppk1
Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
     
 0.761
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
 
   
 0.725
metG
Methionyl-trna synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
     
 0.720
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
Server load: low (8%) [HD]