STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folE2GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate (269 aa)    
Predicted Functional Partners:
queD
6-carboxy-5,6,7,8-tetrahydropterin synthase; queuosine_QueD: queuosine biosynthesis protein QueD
 
  
 0.923
WL94_02585
annotation not available
    
 0.908
WL94_14815
annotation not available
     
  0.900
WL94_09895
annotation not available
     
  0.900
WL94_09900
annotation not available
     
  0.900
WL94_16950
GTP 3',8-cyclase; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family
     
  0.900
WL94_36845
GTP 3',8-cyclase; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family
     
  0.900
folK
folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
    
 0.841
DM42_5450
annotation not available
  
  
 
0.836
folE
folE: GTP cyclohydrolase I
     
 0.809
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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