folP protein (Burkholderia cepacia) - STRING interaction network

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folP

Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives (269 aa)

Predicted Functional Partners:

folK

0.997

folC

0.996

glmM

0.985

DM42_1084

0.983

WL94_30540

0.941

WL94_25240

0.932

WI67_05240

0.836

ribD

0.830

DM42_882

0.797

WI67_21175

0.787

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_1084	WI67_05240	DM42_1084	DM42_745	annotation not available	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	0.558
DM42_1084	WL94_30540	DM42_1084	DM42_2030	annotation not available	Diguanylate cyclase; folB_dom- FolB domain protein	0.472
DM42_1084	folC	DM42_1084	DM42_4091	annotation not available	Bifunctional folylpolyglutamate synthase/dihydrofolate synthase; folC- bifunctional FolC family protein; Belongs to the folylpolyglutamate synthase family	0.718
DM42_1084	folK	DM42_1084	DM42_1081	annotation not available	folK- 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	0.662
DM42_1084	folP	DM42_1084	DM42_423	annotation not available	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	0.983
DM42_1084	ribD	DM42_1084	DM42_881	annotation not available	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.803
DM42_882	WI67_21175	DM42_882	DM42_4257	ribE- riboflavin synthase, alpha subunit	ribE- riboflavin synthase, alpha subunit	0.834
DM42_882	folK	DM42_882	DM42_1081	ribE- riboflavin synthase, alpha subunit	folK- 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	0.426
DM42_882	folP	DM42_882	DM42_423	ribE- riboflavin synthase, alpha subunit	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	0.797
DM42_882	ribD	DM42_882	DM42_881	ribE- riboflavin synthase, alpha subunit	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.997
WI67_05240	DM42_1084	DM42_745	DM42_1084	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	annotation not available	0.558
WI67_05240	folC	DM42_745	DM42_4091	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	Bifunctional folylpolyglutamate synthase/dihydrofolate synthase; folC- bifunctional FolC family protein; Belongs to the folylpolyglutamate synthase family	0.965
WI67_05240	folK	DM42_745	DM42_1081	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folK- 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	0.417
WI67_05240	folP	DM42_745	DM42_423	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	0.836
WI67_05240	ribD	DM42_745	DM42_881	Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.594
WI67_21175	DM42_882	DM42_4257	DM42_882	ribE- riboflavin synthase, alpha subunit	ribE- riboflavin synthase, alpha subunit	0.834
WI67_21175	folP	DM42_4257	DM42_423	ribE- riboflavin synthase, alpha subunit	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	0.787
WI67_21175	ribD	DM42_4257	DM42_881	ribE- riboflavin synthase, alpha subunit	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.961
WL94_25240	WL94_30540	DM42_5601	DM42_2030	annotation not available	Diguanylate cyclase; folB_dom- FolB domain protein	0.900
WL94_25240	folK	DM42_5601	DM42_1081	annotation not available	folK- 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	0.941

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