node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
WI67_00810 | WI67_03825 | DM42_1636 | DM42_1023 | Sda_mono: L-serine ammonia-lyase | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.927 |
WI67_00810 | WL94_02080 | DM42_1636 | DM42_4551 | Sda_mono: L-serine ammonia-lyase | annotation not available | 0.907 |
WI67_00810 | WL94_25215 | DM42_1636 | DM42_5596 | Sda_mono: L-serine ammonia-lyase | Sda_mono: L-serine ammonia-lyase | 0.804 |
WI67_00810 | WL94_31660 | DM42_1636 | DM42_3246 | Sda_mono: L-serine ammonia-lyase | annotation not available | 0.805 |
WI67_00810 | cysE | DM42_1636 | DM42_3004 | Sda_mono: L-serine ammonia-lyase | cysE: serine O-acetyltransferase | 0.907 |
WI67_00810 | glyA2 | DM42_1636 | DM42_5664 | Sda_mono: L-serine ammonia-lyase | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.922 |
WI67_00810 | sds | DM42_1636 | DM42_463 | Sda_mono: L-serine ammonia-lyase | annotation not available | 0.828 |
WI67_00810 | serB | DM42_1636 | DM42_3409 | Sda_mono: L-serine ammonia-lyase | serB: phosphoserine phosphatase SerB | 0.912 |
WI67_03825 | WI67_00810 | DM42_1023 | DM42_1636 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | Sda_mono: L-serine ammonia-lyase | 0.927 |
WI67_03825 | WL94_02080 | DM42_1023 | DM42_4551 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | annotation not available | 0.824 |
WI67_03825 | WL94_25215 | DM42_1023 | DM42_5596 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | Sda_mono: L-serine ammonia-lyase | 0.927 |
WI67_03825 | cysE | DM42_1023 | DM42_3004 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | cysE: serine O-acetyltransferase | 0.824 |
WI67_03825 | glyA2 | DM42_1023 | DM42_5664 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.806 |
WI67_03825 | sds | DM42_1023 | DM42_463 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | annotation not available | 0.909 |
WI67_03825 | serB | DM42_1023 | DM42_3409 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | serB: phosphoserine phosphatase SerB | 0.926 |
WI67_19615 | WL94_02080 | DM42_4550 | DM42_4551 | annotation not available | annotation not available | 0.878 |
WL94_02080 | WI67_00810 | DM42_4551 | DM42_1636 | annotation not available | Sda_mono: L-serine ammonia-lyase | 0.907 |
WL94_02080 | WI67_03825 | DM42_4551 | DM42_1023 | annotation not available | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.824 |
WL94_02080 | WI67_19615 | DM42_4551 | DM42_4550 | annotation not available | annotation not available | 0.878 |
WL94_02080 | WL94_25215 | DM42_4551 | DM42_5596 | annotation not available | Sda_mono: L-serine ammonia-lyase | 0.907 |