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DM42_4682 protein (Burkholderia cepacia) - STRING interaction network
"DM42_4682" - annotation not available in Burkholderia cepacia
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_4682annotation not available (302 aa)    
Predicted Functional Partners:
WL94_38970
annotation not available (477 aa)
   
   
    0.927
WL94_34090
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (432 aa)
     
 
  0.905
WL94_31925
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (448 aa)
     
 
  0.905
cpdB
annotation not available (689 aa)
     
 
  0.905
purH
Bifunctional purine biosynthesis protein PurH; purH- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (521 aa)
         
  0.905
rdgB
dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family (208 aa)
         
  0.905
purB
purB- adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (462 aa)
         
  0.904
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (206 aa)
         
  0.903
dgt
Deoxyguanosinetriphosphate triphosphohydrolase-like protein; dGTP_triPase- dGTPase family protein; Belongs to the dGTPase family. Type 2 subfamily (402 aa)
       
    0.903
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (188 aa)
     
 
    0.902
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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