Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Fusion
Genes that are sometimes fused into single open reading frames.
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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_4844
annotation not available (165 aa)
Predicted Functional Partners:
DM42_7387
annotation not available
0.657
WL94_37395
Uncharacterized protein
0.561
WL94_33910
DNA-binding protein
0.443
yidC
Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
0.436
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1
node2
node1 accession
node2 accession
node1 annotation
node2 annotation
score
DM42_1572
DM42_4844
DM42_1572
DM42_4844
annotation not available
annotation not available
0.404
DM42_4844
DM42_1572
DM42_4844
DM42_1572
annotation not available
annotation not available
0.404
DM42_4844
DM42_7387
DM42_4844
DM42_7387
annotation not available
annotation not available
0.657
DM42_4844
WL94_33910
DM42_4844
DM42_6533
annotation not available
DNA-binding protein
0.443
DM42_4844
WL94_37395
DM42_4844
DM42_5340
annotation not available
Uncharacterized protein
0.561
DM42_4844
WL94_38795
DM42_4844
DM42_5974
annotation not available
annotation not available
0.414
DM42_4844
htpG
DM42_4844
DM42_2714
annotation not available
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity
0.426
DM42_4844
yidC
DM42_4844
DM42_1790
annotation not available
Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
0.436
DM42_7387
DM42_4844
DM42_7387
DM42_4844
annotation not available
annotation not available
0.657
DM42_7387
WL94_33910
DM42_7387
DM42_6533
annotation not available
DNA-binding protein
0.694
DM42_7387
WL94_37395
DM42_7387
DM42_5340
annotation not available
Uncharacterized protein
0.613
DM42_7387
WL94_38795
DM42_7387
DM42_5974
annotation not available
annotation not available
0.764
WL94_33910
DM42_4844
DM42_6533
DM42_4844
DNA-binding protein
annotation not available
0.443
WL94_33910
DM42_7387
DM42_6533
DM42_7387
DNA-binding protein
annotation not available
0.694
WL94_33910
WL94_38795
DM42_6533
DM42_5974
DNA-binding protein
annotation not available
0.768
WL94_37395
DM42_4844
DM42_5340
DM42_4844
Uncharacterized protein
annotation not available
0.561
WL94_37395
DM42_7387
DM42_5340
DM42_7387
Uncharacterized protein
annotation not available
0.613
WL94_38795
DM42_4844
DM42_5974
DM42_4844
annotation not available
annotation not available
0.414
WL94_38795
DM42_7387
DM42_5974
DM42_7387
annotation not available
annotation not available
0.764
WL94_38795
WL94_33910
DM42_5974
DM42_6533
annotation not available
DNA-binding protein
0.768
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Network Stats
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Functional enrichments in your networkNote: some enrichments may be expected here (why?) explain columns
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis, the following statistical background is assumed: