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WL94_10250 protein (Burkholderia cepacia) - STRING interaction network
"WL94_10250" - 2-isopropylmalate synthase in Burkholderia cepacia
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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WL94_102502-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily (569 aa)    
Predicted Functional Partners:
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate; Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily (469 aa)
 
  0.987
WI67_22900
ilvD- dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family (619 aa)
 
 
  0.970
WL94_04345
ilvD- dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family (557 aa)
   
 
  0.964
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate; Belongs to the LeuD family. LeuD type 1 subfamily (216 aa)
 
 
  0.956
WL94_05875
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (299 aa)
   
  0.949
DM42_4992
ac_ald_DH_ac- acetaldehyde dehydrogenase (306 aa)
   
  0.949
ilvE
Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family (307 aa)
   
  0.931
WL94_39140
annotation not available (326 aa)
   
  0.917
acoC
annotation not available (371 aa)
   
 
  0.913
WL94_31655
annotation not available (412 aa)
     
 
  0.908
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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