DM42_5035 protein (Burkholderia cepacia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DM42_5035

annotation not available (375 aa)

Predicted Functional Partners:

prmA

0.812

grpE

0.706

epaO

0.691

htpG

0.660

DM42_118

0.643

dnaK

0.634

WL94_16270

0.634

hscA

0.634

WL94_10720

0.634

WL94_10715

0.634

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_118	DM42_5035	DM42_118	DM42_5035	annotation not available	annotation not available	0.643
DM42_118	epaO	DM42_118	DM42_5960	annotation not available	spaO_YscQ: type III secretion apparatus protein, YscQ/HrcQ family	0.779
DM42_5035	DM42_118	DM42_5035	DM42_118	annotation not available	annotation not available	0.643
DM42_5035	WL94_10715	DM42_5035	DM42_4489	annotation not available	annotation not available	0.634
DM42_5035	WL94_10720	DM42_5035	DM42_4488	annotation not available	annotation not available	0.634
DM42_5035	WL94_16270	DM42_5035	DM42_1340	annotation not available	annotation not available	0.634
DM42_5035	dnaK	DM42_5035	DM42_1086	annotation not available	Chaperone protein DnaK; Acts as a chaperone	0.634
DM42_5035	epaO	DM42_5035	DM42_5960	annotation not available	spaO_YscQ: type III secretion apparatus protein, YscQ/HrcQ family	0.691
DM42_5035	grpE	DM42_5035	DM42_1088	annotation not available	Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent [...]	0.706
DM42_5035	hscA	DM42_5035	DM42_2966	annotation not available	Chaperone protein HscA homolog; Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	0.634
DM42_5035	htpG	DM42_5035	DM42_2714	annotation not available	Chaperone protein HtpG; Molecular chaperone. Has ATPase activity	0.660
DM42_5035	prmA	DM42_5035	DM42_1238	annotation not available	Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11	0.812
WL94_10715	DM42_5035	DM42_4489	DM42_5035	annotation not available	annotation not available	0.634
WL94_10715	WL94_10720	DM42_4489	DM42_4488	annotation not available	annotation not available	0.904
WL94_10715	grpE	DM42_4489	DM42_1088	annotation not available	Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent [...]	0.860
WL94_10715	htpG	DM42_4489	DM42_2714	annotation not available	Chaperone protein HtpG; Molecular chaperone. Has ATPase activity	0.714
WL94_10720	DM42_5035	DM42_4488	DM42_5035	annotation not available	annotation not available	0.634
WL94_10720	WL94_10715	DM42_4488	DM42_4489	annotation not available	annotation not available	0.904
WL94_10720	grpE	DM42_4488	DM42_1088	annotation not available	Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent [...]	0.860
WL94_10720	htpG	DM42_4488	DM42_2714	annotation not available	Chaperone protein HtpG; Molecular chaperone. Has ATPase activity	0.714

page 1 of 3

Network

Neighborhood

Experiments

Fusion

Textmining

Cooccurrence

Databases

Coexpression

© STRING Consortium 2020

Credits

Access

Info

About