node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
WI67_04835 | WL94_13215 | DM42_827 | DM42_7379 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | annotation not available | 0.649 |
WI67_04835 | dnaN | DM42_827 | DM42_1785 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as [...] | 0.963 |
WI67_04835 | polA | DM42_827 | DM42_4183 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.968 |
WI67_04835 | recA | DM42_827 | DM42_2420 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage | 0.754 |
WI67_04835 | recB | DM42_827 | DM42_506 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | RecBCD enzyme subunit RecB; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holo [...] | 0.773 |
WI67_04835 | recC | DM42_827 | DM42_507 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | RecBCD enzyme subunit RecC; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holo [...] | 0.555 |
WI67_04835 | recD | DM42_827 | DM42_505 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | recD: exodeoxyribonuclease V, alpha subunit | 0.655 |
WI67_04835 | recQ | DM42_827 | DM42_1479 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | recQ: ATP-dependent DNA helicase RecQ | 0.646 |
WI67_04835 | recR | DM42_827 | DM42_3275 | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO | 0.685 |
WL94_13215 | WI67_04835 | DM42_7379 | DM42_827 | annotation not available | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | 0.649 |
WL94_13215 | polA | DM42_7379 | DM42_4183 | annotation not available | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.712 |
WL94_13215 | recA | DM42_7379 | DM42_2420 | annotation not available | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage | 0.837 |
WL94_13215 | recB | DM42_7379 | DM42_506 | annotation not available | RecBCD enzyme subunit RecB; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holo [...] | 0.635 |
WL94_13215 | recD | DM42_7379 | DM42_505 | annotation not available | recD: exodeoxyribonuclease V, alpha subunit | 0.679 |
WL94_13215 | recQ | DM42_7379 | DM42_1479 | annotation not available | recQ: ATP-dependent DNA helicase RecQ | 0.670 |
WL94_17470 | polA | DM42_504 | DM42_4183 | annotation not available | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity | 0.673 |
WL94_17470 | recB | DM42_504 | DM42_506 | annotation not available | RecBCD enzyme subunit RecB; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holo [...] | 0.853 |
WL94_17470 | recC | DM42_504 | DM42_507 | annotation not available | RecBCD enzyme subunit RecC; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holo [...] | 0.851 |
WL94_17470 | recD | DM42_504 | DM42_505 | annotation not available | recD: exodeoxyribonuclease V, alpha subunit | 0.851 |
dnaN | WI67_04835 | DM42_1785 | DM42_827 | Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as [...] | Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein | 0.963 |