Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

WI67_17370

annotation not available (248 aa)

Predicted Functional Partners:

WL94_15815

0.642

WI67_17375

0.634

hemN

0.529

rpoC

0.478

rpoA

0.468

rpoS

0.467

rpoB

0.457

DM42_5617

0.456

rpoD

0.456

DM42_3834

0.456

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but resolution at 400 dpi

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_3834	WI67_17370	DM42_3834	DM42_5098	sigma70-ECF- RNA polymerase sigma factor, sigma-70 family protein	annotation not available	0.456
DM42_3834	rpoA	DM42_3834	DM42_1447	sigma70-ECF- RNA polymerase sigma factor, sigma-70 family protein	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	0.835
DM42_3834	rpoB	DM42_3834	DM42_1481	sigma70-ECF- RNA polymerase sigma factor, sigma-70 family protein	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	0.872
DM42_3834	rpoC	DM42_3834	DM42_1480	sigma70-ECF- RNA polymerase sigma factor, sigma-70 family protein	DNA-directed RNA polymerase subunit beta’; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	0.848
DM42_5617	WI67_17370	DM42_5617	DM42_5098	sigma70-ECF- RNA polymerase sigma factor, sigma-70 family protein	annotation not available	0.456
DM42_5617	rpoA	DM42_5617	DM42_1447	sigma70-ECF- RNA polymerase sigma factor, sigma-70 family protein	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	0.864
DM42_5617	rpoB	DM42_5617	DM42_1481	sigma70-ECF- RNA polymerase sigma factor, sigma-70 family protein	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	0.895
DM42_5617	rpoC	DM42_5617	DM42_1480	sigma70-ECF- RNA polymerase sigma factor, sigma-70 family protein	DNA-directed RNA polymerase subunit beta’; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	0.873
WI67_17370	DM42_3834	DM42_5098	DM42_3834	annotation not available	sigma70-ECF- RNA polymerase sigma factor, sigma-70 family protein	0.456
WI67_17370	DM42_5617	DM42_5098	DM42_5617	annotation not available	sigma70-ECF- RNA polymerase sigma factor, sigma-70 family protein	0.456
WI67_17370	WI67_17375	DM42_5098	DM42_5097	annotation not available	annotation not available	0.634
WI67_17370	WL94_15815	DM42_5098	DM42_1419	annotation not available	annotation not available	0.642
WI67_17370	hemN	DM42_5098	DM42_916	annotation not available	hemN- oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family	0.529
WI67_17370	rpoA	DM42_5098	DM42_1447	annotation not available	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	0.468
WI67_17370	rpoB	DM42_5098	DM42_1481	annotation not available	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	0.457
WI67_17370	rpoC	DM42_5098	DM42_1480	annotation not available	DNA-directed RNA polymerase subunit beta’; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	0.478
WI67_17370	rpoD	DM42_5098	DM42_4169	annotation not available	RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	0.456
WI67_17370	rpoS	DM42_5098	DM42_3280	annotation not available	rpoS_proteo- RNA polymerase sigma factor RpoS	0.467
WI67_17375	WI67_17370	DM42_5097	DM42_5098	annotation not available	annotation not available	0.634
WL94_15815	WI67_17370	DM42_1419	DM42_5098	annotation not available	annotation not available	0.642

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Coexpression

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