STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_5131Tartrate dehydrogenase/decarboxylase / d-malate dehydrogenase; TTC: tartrate dehydrogenase (361 aa)    
Predicted Functional Partners:
DM42_4344
Tartrate dehydrogenase/decarboxylase / d-malate dehydrogenase; TTC: tartrate dehydrogenase
  
  
 
0.906
leuC
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate
 
 0.904
DM42_6773
Tartrate dehydrogenase/decarboxylase / d-malate dehydrogenase; TTC: tartrate dehydrogenase
  
  
 
0.902
DM42_1419
annotation not available
  
  
 0.893
ilvN
Acolac_sm: acetolactate synthase, small subunit
 
 
 0.838
ilvB
Acolac_lg: acetolactate synthase, large subunit, biosynthetic type
 0.834
leuD
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate
  
 0.829
sucA
2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component
  
 0.801
sucD
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
  
 0.778
DM42_1639
Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family
 0.776
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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