STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_5204Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family (452 aa)    
Predicted Functional Partners:
hemA
Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)
 
 0.952
hemB
Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family
 
 
 0.950
hemL
hemL: glutamate-1-semialdehyde-2,1-aminomutase
  
  
 
0.829
hemDX
annotation not available
  
 
 0.781
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate
  
  
 0.729
DM42_5765
Non-ribosomal peptide synthetase; AA-adenyl-dom: amino acid adenylation domain protein
    
 0.572
DM42_1419
annotation not available
  
  
 0.563
cobJ
Cobalt-precorrin 5a hydrolase / precorrin-3b c17-methyltransferase; Cobalamin biosynthesis protein CbiG; cobJ_cbiH: precorrin-3B C17-methyltransferase
     
 0.513
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
 
  
 0.510
cbiT
cbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit
     
 0.502
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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