Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

WI67_31920

annotation not available (298 aa)

Predicted Functional Partners:

dapB

0.963

asd

0.925

WL94_00650

0.883

DM42_5220

0.850

DM42_6459

0.765

WL94_31660

0.717

WI67_31930

0.673

DM42_6447

0.654

DM42_6440

0.536

WI67_24130

0.429

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but resolution at 400 dpi

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_5220	WI67_31920	DM42_5220	DM42_5219	annotation not available	annotation not available	0.850
DM42_5220	WI67_31930	DM42_5220	DM42_5217	annotation not available	annotation not available	0.504
DM42_5220	WL94_00650	DM42_5220	DM42_5218	annotation not available	Class II Aldolase and Adducin N-terminal domain protein	0.678
DM42_6440	DM42_6447	DM42_6440	DM42_6447	Class II Aldolase and Adducin N-terminal domain protein	Class II Aldolase and Adducin N-terminal domain protein	0.833
DM42_6440	WI67_31920	DM42_6440	DM42_5219	Class II Aldolase and Adducin N-terminal domain protein	annotation not available	0.536
DM42_6440	WL94_00650	DM42_6440	DM42_5218	Class II Aldolase and Adducin N-terminal domain protein	Class II Aldolase and Adducin N-terminal domain protein	0.810
DM42_6447	DM42_6440	DM42_6447	DM42_6440	Class II Aldolase and Adducin N-terminal domain protein	Class II Aldolase and Adducin N-terminal domain protein	0.833
DM42_6447	WI67_31920	DM42_6447	DM42_5219	Class II Aldolase and Adducin N-terminal domain protein	annotation not available	0.654
DM42_6447	WI67_31930	DM42_6447	DM42_5217	Class II Aldolase and Adducin N-terminal domain protein	annotation not available	0.413
DM42_6447	WL94_00650	DM42_6447	DM42_5218	Class II Aldolase and Adducin N-terminal domain protein	Class II Aldolase and Adducin N-terminal domain protein	0.803
DM42_6459	WI67_31920	DM42_6459	DM42_5219	annotation not available	annotation not available	0.765
DM42_6459	WL94_31660	DM42_6459	DM42_3246	annotation not available	annotation not available	0.830
DM42_6459	asd	DM42_6459	DM42_4100	annotation not available	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family	0.939
DM42_6459	dapB	DM42_6459	DM42_1192	annotation not available	4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	0.407
WI67_24130	WI67_31920	DM42_3601	DM42_5219	annotation not available	annotation not available	0.429
WI67_31920	DM42_5220	DM42_5219	DM42_5220	annotation not available	annotation not available	0.850
WI67_31920	DM42_6440	DM42_5219	DM42_6440	annotation not available	Class II Aldolase and Adducin N-terminal domain protein	0.536
WI67_31920	DM42_6447	DM42_5219	DM42_6447	annotation not available	Class II Aldolase and Adducin N-terminal domain protein	0.654
WI67_31920	DM42_6459	DM42_5219	DM42_6459	annotation not available	annotation not available	0.765
WI67_31920	WI67_24130	DM42_5219	DM42_3601	annotation not available	annotation not available	0.429

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