STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_522Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family (457 aa)    
Predicted Functional Partners:
DM42_523
Multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
 0.985
DM42_524
Acrb/acrd/acrf family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
 0.984
macB
Macrolide transport system atp-binding/permease protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides
  
 0.909
DM42_1729
outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein
 
 0.826
DM42_4607
2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein
 0.818
DM42_6634
2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein
 0.808
ceoB
2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein
 0.806
DM42_6056
2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein
 0.806
acrB
annotation not available
 0.801
DM42_7396
2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein
 0.800
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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