STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prpC2-methylcitrate synthase/citrate synthase II family protein; Belongs to the citrate synthase family (390 aa)    
Predicted Functional Partners:
prpD
prpD: 2-methylcitrate dehydratase
 0.996
acnD
2-methylcitrate dehydratase (2-methyl-trans-aconitate forming); 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent
 
 0.995
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
 
 0.976
pta
Pta: phosphate acetyltransferase
  
 
 0.955
bkdB
annotation not available
  
 0.948
Acs
Acetyl-coa synthetase; ac_CoA_lig_AcsA: acetate--CoA ligase
  
 0.945
DM42_404
annotation not available
  
 0.945
DM42_5616
Acetyl-coa synthetase; Acetyl-coenzyme A synthetase; ac_CoA_lig_AcsA: acetate--CoA ligase
  
 0.945
DM42_5799
annotation not available
  
 0.945
DM42_7365
annotation not available
  
 0.945
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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