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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acnD2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent (864 aa)    
Predicted Functional Partners:
prpF
3-methylitaconate isomerase; prpF: putative AcnD-accessory protein PrpF
 
 
 0.997
WL94_00340
cit_synth_II: 2-methylcitrate synthase/citrate synthase II family protein; Belongs to the citrate synthase family
 
 0.993
prpD
prpD: 2-methylcitrate dehydratase
  
 
 0.956
prpB
2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate; Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family
 
 
 0.870
gltA
cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family
 
 
 0.755
WI67_11925
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)- malate; Belongs to the class-I fumarase family
  
  
 0.701
DM42_2533
annotation not available
 
 
 0.694
WL94_30910
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family
  
  
 0.671
DM42_4917
PEP_synth: phosphoenolpyruvate synthase
  
  
 0.671
WL94_15815
annotation not available
  
  
 0.668
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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