STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabVEnoyl-[acyl-carrier protein] reductase / trans-2-enoyl-coa reductase (nad+); Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) (400 aa)    
Predicted Functional Partners:
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase fabz; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
  
 
 0.947
DM42_6948
3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl synthase, C-terminal domain protein
  
 
 0.928
fabF
Beta-ketoacyl-acyl-carrier-protein synthase ii; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
  
 
 0.928
DM42_2304
3-oxoacyl-ACP synthase; Thiolase, N-terminal domain protein; Belongs to the beta-ketoacyl-ACP synthases family
  
 
 0.919
DM42_2061
annotation not available
    
  0.903
DM42_1299
Enoyl-coa hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family
     
  0.900
DM42_2073
annotation not available
     
  0.900
echA15
Enoyl-coa hydratase echa15; Belongs to the enoyl-CoA hydratase/isomerase family
     
  0.900
DM42_4992
Acetaldehyde/propanal dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds
     
  0.900
DM42_6324
annotation not available
     
  0.900
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
Server load: low (22%) [HD]