Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

choW

ABC_choXWV_perm- choline ABC transporter, permease protein (298 aa)

Predicted Functional Partners:

WI67_30070

0.999

WI67_29450

0.997

WI67_30055

0.988

WL94_35605

0.987

WL94_35505

0.986

WL94_01220

0.981

WI67_30060

0.689

polA

0.519

DM42_6603

0.493

DM42_6601

0.443

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but resolution at 400 dpi

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_6601	DM42_6603	DM42_6601	DM42_6603	proV- glycine betaine/L-proline transport ATP binding subunit	annotation not available	0.997
DM42_6601	choW	DM42_6601	DM42_5577	proV- glycine betaine/L-proline transport ATP binding subunit	ABC_choXWV_perm- choline ABC transporter, permease protein	0.443
DM42_6603	DM42_6601	DM42_6603	DM42_6601	annotation not available	proV- glycine betaine/L-proline transport ATP binding subunit	0.997
DM42_6603	choW	DM42_6603	DM42_5577	annotation not available	ABC_choXWV_perm- choline ABC transporter, permease protein	0.493
WI67_29450	WI67_30070	DM42_5673	DM42_5576	annotation not available	Glycine betaine/L-proline ABC transporter ATP-binding protein; proV- glycine betaine/L-proline transport ATP binding subunit	0.984
WI67_29450	choW	DM42_5673	DM42_5577	annotation not available	ABC_choXWV_perm- choline ABC transporter, permease protein	0.997
WI67_30055	WI67_30060	DM42_5579	DM42_5578	ABC_choline_bnd- choline ABC transporter, periplasmic binding family protein	annotation not available	0.790
WI67_30055	WI67_30070	DM42_5579	DM42_5576	ABC_choline_bnd- choline ABC transporter, periplasmic binding family protein	Glycine betaine/L-proline ABC transporter ATP-binding protein; proV- glycine betaine/L-proline transport ATP binding subunit	0.987
WI67_30055	choW	DM42_5579	DM42_5577	ABC_choline_bnd- choline ABC transporter, periplasmic binding family protein	ABC_choXWV_perm- choline ABC transporter, permease protein	0.988
WI67_30060	WI67_30055	DM42_5578	DM42_5579	annotation not available	ABC_choline_bnd- choline ABC transporter, periplasmic binding family protein	0.790
WI67_30060	WI67_30070	DM42_5578	DM42_5576	annotation not available	Glycine betaine/L-proline ABC transporter ATP-binding protein; proV- glycine betaine/L-proline transport ATP binding subunit	0.682
WI67_30060	WL94_01220	DM42_5578	DM42_4741	annotation not available	ABC_choline_bnd- choline ABC transporter, periplasmic binding family protein	0.521
WI67_30060	WL94_35505	DM42_5578	DM42_5696	annotation not available	ABC_choline_bnd- choline ABC transporter, periplasmic binding family protein	0.526
WI67_30060	WL94_35605	DM42_5578	DM42_5678	annotation not available	ABC_choline_bnd- choline ABC transporter, periplasmic binding family protein	0.492
WI67_30060	choW	DM42_5578	DM42_5577	annotation not available	ABC_choXWV_perm- choline ABC transporter, permease protein	0.689
WI67_30070	WI67_29450	DM42_5576	DM42_5673	Glycine betaine/L-proline ABC transporter ATP-binding protein; proV- glycine betaine/L-proline transport ATP binding subunit	annotation not available	0.984
WI67_30070	WI67_30055	DM42_5576	DM42_5579	Glycine betaine/L-proline ABC transporter ATP-binding protein; proV- glycine betaine/L-proline transport ATP binding subunit	ABC_choline_bnd- choline ABC transporter, periplasmic binding family protein	0.987
WI67_30070	WI67_30060	DM42_5576	DM42_5578	Glycine betaine/L-proline ABC transporter ATP-binding protein; proV- glycine betaine/L-proline transport ATP binding subunit	annotation not available	0.682
WI67_30070	WL94_01220	DM42_5576	DM42_4741	Glycine betaine/L-proline ABC transporter ATP-binding protein; proV- glycine betaine/L-proline transport ATP binding subunit	ABC_choline_bnd- choline ABC transporter, periplasmic binding family protein	0.979
WI67_30070	WL94_35505	DM42_5576	DM42_5696	Glycine betaine/L-proline ABC transporter ATP-binding protein; proV- glycine betaine/L-proline transport ATP binding subunit	ABC_choline_bnd- choline ABC transporter, periplasmic binding family protein	0.980

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Coexpression

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