STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pqqCCoenzyme pqq biosynthesis protein c; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ (238 aa)    
Predicted Functional Partners:
pqqB
Pyrroloquinoline quinone biosynthesis protein b; May be involved in the transport of PQQ or its precursor to the periplasm
  
 0.996
pqqE
Coenzyme pqq biosynthesis enzyme pqqe; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ)
 
  
 0.992
pqqD
Pyrroloquinoline quinone biosynthesis protein d; PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD
 
  
 0.985
DM42_5620
Pyrrolo-quinoline quinone; PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family protein
 
   
 0.862
DM42_5621
annotation not available
  
     0.650
phoB
Two-component system, ompr family, phosphate regulon response regulator phob; Two-component system response regulator; phoB: phosphate regulon transcriptional regulatory protein PhoB
      
 0.505
pstS
Phosphate abc transporter, phosphate-binding protein psts; Part of the ABC transporter complex PstSACB involved in phosphate import
   
  
 0.493
phoU
Phosphate transport system regulatory protein phou; Plays a role in the regulation of phosphate uptake
      
 0.487
pstB
Phosphate transport system atp-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
      
 0.483
pstA
3a0107s02c: phosphate ABC transporter, permease protein PstA
      
 0.483
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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