Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

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Experiments

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[Homology]

Score

WL94_35360

Type IV secretion protein Rhs; Rhs_assc_core- RHS repeat-associated core domain protein (473 aa)

Predicted Functional Partners:

DM42_6971

0.753

DM42_395

0.684

WL94_35370

0.670

DM42_5738

0.642

DM42_7346

0.606

DM42_845

0.538

DM42_5104

0.498

DM42_1366

0.472

WI67_02135

0.463

dltA

0.441

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

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same PNG format, but resolution at 400 dpi

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_1366	DM42_395	DM42_1366	DM42_395	Type VI secretion protein	vgr_GE- Rhs element Vgr family protein	0.806
DM42_1366	DM42_5104	DM42_1366	DM42_5104	Type VI secretion protein	vgr_GE- Rhs element Vgr family protein	0.842
DM42_1366	DM42_7346	DM42_1366	DM42_7346	Type VI secretion protein	vgr_GE- Rhs element Vgr family protein	0.845
DM42_1366	DM42_845	DM42_1366	DM42_845	Type VI secretion protein	vgr_GE- Rhs element Vgr family protein	0.844
DM42_1366	WI67_02135	DM42_1366	DM42_1365	Type VI secretion protein	EvpB family type VI secretion protein	0.999
DM42_1366	WL94_35360	DM42_1366	DM42_5740	Type VI secretion protein	Type IV secretion protein Rhs; Rhs_assc_core- RHS repeat-associated core domain protein	0.472
DM42_1366	WL94_35370	DM42_1366	DM42_5737	Type VI secretion protein	Type VI secretion protein; vgr_GE- Rhs element Vgr family protein	0.801
DM42_395	DM42_1366	DM42_395	DM42_1366	vgr_GE- Rhs element Vgr family protein	Type VI secretion protein	0.806
DM42_395	WI67_02135	DM42_395	DM42_1365	vgr_GE- Rhs element Vgr family protein	EvpB family type VI secretion protein	0.806
DM42_395	WL94_35360	DM42_395	DM42_5740	vgr_GE- Rhs element Vgr family protein	Type IV secretion protein Rhs; Rhs_assc_core- RHS repeat-associated core domain protein	0.684
DM42_5104	DM42_1366	DM42_5104	DM42_1366	vgr_GE- Rhs element Vgr family protein	Type VI secretion protein	0.842
DM42_5104	DM42_7346	DM42_5104	DM42_7346	vgr_GE- Rhs element Vgr family protein	vgr_GE- Rhs element Vgr family protein	0.489
DM42_5104	WI67_02135	DM42_5104	DM42_1365	vgr_GE- Rhs element Vgr family protein	EvpB family type VI secretion protein	0.832
DM42_5104	WL94_35360	DM42_5104	DM42_5740	vgr_GE- Rhs element Vgr family protein	Type IV secretion protein Rhs; Rhs_assc_core- RHS repeat-associated core domain protein	0.498
DM42_5738	DM42_7346	DM42_5738	DM42_7346	Conserved hypothetical protein	vgr_GE- Rhs element Vgr family protein	0.554
DM42_5738	WL94_35360	DM42_5738	DM42_5740	Conserved hypothetical protein	Type IV secretion protein Rhs; Rhs_assc_core- RHS repeat-associated core domain protein	0.642
DM42_5738	WL94_35370	DM42_5738	DM42_5737	Conserved hypothetical protein	Type VI secretion protein; vgr_GE- Rhs element Vgr family protein	0.907
DM42_6971	WL94_35360	DM42_6971	DM42_5740	annotation not available	Type IV secretion protein Rhs; Rhs_assc_core- RHS repeat-associated core domain protein	0.753
DM42_6971	dltA	DM42_6971	DM42_54	annotation not available	Non-ribosomal peptide synthetase; D-ala-DACP-lig- D-alanine--poly(phosphoribitol) ligase, subunit 1	0.470
DM42_7346	DM42_1366	DM42_7346	DM42_1366	vgr_GE- Rhs element Vgr family protein	Type VI secretion protein	0.845

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