STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
galEUdp-glucose 4-epimerase gale; Belongs to the NAD(P)-dependent epimerase/dehydratase family (329 aa)    
Predicted Functional Partners:
DM42_5968
annotation not available
0.988
DM42_7127
annotation not available
 
0.925
DM42_5966
UDP-glucose 6-dehydrogenase; NDP-sugDHase: nucleotide sugar dehydrogenase family protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family
 
  
 0.835
DM42_5965
annotation not available
 
  
 0.814
DM42_1061
annotation not available
  
  
 0.682
pgaC
Poly-beta-1,6-N-acetyl-D-glucosamine synthase; pgaC_IcaA: poly-beta-1,6 N-acetyl-D-glucosamine synthase
  
  
 0.597
purL
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
     
 0.592
rplR
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
     
 0.577
gidA
Trna uridine 5-carboxymethylaminomethyl modification enzyme gida; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
      
 0.557
rplW
Large subunit ribosomal protein l23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
     
 0.545
Your Current Organism:
Burkholderia cepacia
NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717
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