node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DM42_4865 | WI67_12270 | DM42_4865 | DM42_2802 | annotation not available | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | 0.900 |
DM42_4865 | WL94_05875 | DM42_4865 | DM42_6344 | annotation not available | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds | 0.907 |
DM42_4865 | WL94_10250 | DM42_4865 | DM42_4969 | annotation not available | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily | 0.900 |
DM42_4865 | WL94_13975 | DM42_4865 | DM42_2257 | annotation not available | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily | 0.900 |
DM42_4865 | acoC | DM42_4865 | DM42_3263 | annotation not available | annotation not available | 0.917 |
DM42_4865 | pta | DM42_4865 | DM42_3910 | annotation not available | Pta: phosphate acetyltransferase | 0.824 |
DM42_4991 | WI67_25005 | DM42_4991 | DM42_6345 | 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase | catechol_dmpE: 2-oxopent-4-enoate hydratase | 0.989 |
DM42_4991 | WI67_25015 | DM42_4991 | DM42_6343 | 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds | 0.901 |
DM42_4991 | WL94_05875 | DM42_4991 | DM42_6344 | 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds | 0.992 |
WI67_12270 | DM42_4865 | DM42_2802 | DM42_4865 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | annotation not available | 0.900 |
WI67_12270 | WL94_05875 | DM42_2802 | DM42_6344 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds | 0.949 |
WI67_12270 | WL94_10250 | DM42_2802 | DM42_4969 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily | 0.816 |
WI67_12270 | WL94_13975 | DM42_2802 | DM42_2257 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily | 0.816 |
WI67_12270 | acoC | DM42_2802 | DM42_3263 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | annotation not available | 0.913 |
WI67_12270 | pta | DM42_2802 | DM42_3910 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily | Pta: phosphate acetyltransferase | 0.900 |
WI67_25005 | DM42_4991 | DM42_6345 | DM42_4991 | catechol_dmpE: 2-oxopent-4-enoate hydratase | 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase | 0.989 |
WI67_25005 | WI67_25015 | DM42_6345 | DM42_6343 | catechol_dmpE: 2-oxopent-4-enoate hydratase | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds | 0.997 |
WI67_25005 | WL94_05875 | DM42_6345 | DM42_6344 | catechol_dmpE: 2-oxopent-4-enoate hydratase | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds | 0.965 |
WI67_25015 | DM42_4991 | DM42_6343 | DM42_4991 | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds | 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase | 0.901 |
WI67_25015 | WI67_25005 | DM42_6343 | DM42_6345 | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds | catechol_dmpE: 2-oxopent-4-enoate hydratase | 0.997 |