Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
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Fusion
Genes that are sometimes fused into single open reading frames.
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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM42_6412
annotation not available (451 aa)
Predicted Functional Partners:
DM42_6413
annotation not available
0.853
DM42_6411
annotation not available
0.847
DM42_6410
annotation not available
0.845
DM42_6414
annotation not available
0.823
DM42_4938
Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein
0.800
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
0.800
WL94_33080
Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein
0.800
DM42_6416
annotation not available
0.795
DM42_6417
annotation not available
0.793
WL94_38270
Non-ribosomal peptide synthetase; AA-adenyl-dom: amino acid adenylation domain protein