Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
annotation not available (390 aa)
Predicted Functional Partners:
annotation not available (223 aa)
annotation not available (475 aa)
annotation not available (411 aa)
annotation not available (488 aa)
Sodium-alanine symporter; agcS- amino acid carrier family protein (496 aa)
2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate; Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family (297 aa)
annotation not available (1567 aa)
annotation not available (289 aa)
annotation not available (187 aa)
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate (328 aa)