Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

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[Homology]

Score

DM42_7101

Conserved hypothetical protein (128 aa)

Predicted Functional Partners:

DM42_7102

0.865

WL94_37210

0.694

katE

0.535

WL94_37205

0.522

DM42_7099

0.408

Your Current Organism:

Burkholderia cepacia

NCBI taxonomy Id: 292
Other names: ATCC 25416, B. cepacia, Burkholderia cepacia, Burkholderia cepacia genomovar I, CCUG 12691, CCUG 13226, CFBP 2227, CIP 80.24, DSM 7288, ICMP 5796, IFO 14074, JCM 5964, NBRC 14074, NCCB 76047, NCPPB 2993, NCTC 10743, NRRL B-14810, Pseudomonas cepacia, Pseudomonas kingii, Pseudomonas multivorans, strain 717-ICPB 25, strain Ballard 717

Export your current network:

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same PNG format, but resolution at 400 dpi

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM42_7099	DM42_7101	DM42_7099	DM42_7101	Ku_bact- Ku protein	Conserved hypothetical protein	0.408
DM42_7099	DM42_7102	DM42_7099	DM42_7102	Ku_bact- Ku protein	Conserved hypothetical protein	0.512
DM42_7099	katE	DM42_7099	DM42_7100	Ku_bact- Ku protein	Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide	0.787
DM42_7101	DM42_7099	DM42_7101	DM42_7099	Conserved hypothetical protein	Ku_bact- Ku protein	0.408
DM42_7101	DM42_7102	DM42_7101	DM42_7102	Conserved hypothetical protein	Conserved hypothetical protein	0.865
DM42_7101	WL94_37205	DM42_7101	DM42_7104	Conserved hypothetical protein	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	0.522
DM42_7101	WL94_37210	DM42_7101	DM42_7103	Conserved hypothetical protein	Uncharacterized protein	0.694
DM42_7101	katE	DM42_7101	DM42_7100	Conserved hypothetical protein	Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide	0.535
DM42_7102	DM42_7099	DM42_7102	DM42_7099	Conserved hypothetical protein	Ku_bact- Ku protein	0.512
DM42_7102	DM42_7101	DM42_7102	DM42_7101	Conserved hypothetical protein	Conserved hypothetical protein	0.865
DM42_7102	WL94_37205	DM42_7102	DM42_7104	Conserved hypothetical protein	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	0.522
DM42_7102	WL94_37210	DM42_7102	DM42_7103	Conserved hypothetical protein	Uncharacterized protein	0.732
DM42_7102	katE	DM42_7102	DM42_7100	Conserved hypothetical protein	Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide	0.529
WL94_37205	DM42_7101	DM42_7104	DM42_7101	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	Conserved hypothetical protein	0.522
WL94_37205	DM42_7102	DM42_7104	DM42_7102	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	Conserved hypothetical protein	0.522
WL94_37205	WL94_37210	DM42_7104	DM42_7103	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	Uncharacterized protein	0.627
WL94_37205	katE	DM42_7104	DM42_7100	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide	0.475
WL94_37210	DM42_7101	DM42_7103	DM42_7101	Uncharacterized protein	Conserved hypothetical protein	0.694
WL94_37210	DM42_7102	DM42_7103	DM42_7102	Uncharacterized protein	Conserved hypothetical protein	0.732
WL94_37210	WL94_37205	DM42_7103	DM42_7104	Uncharacterized protein	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	0.627

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