Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABF65025.1
annotation not available (157 aa)
Predicted Functional Partners:
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family
0.855
carA
annotation not available
0.669
ABF65027.1
annotation not available
0.459
Your Current Organism:
Ruegeria sp. TM1040
NCBI taxonomy Id: 292414 Other names: R. sp. TM1040, Ruegeria sp. TM1040, Silicibacter sp. TM1040
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1
node2
node1 accession
node2 accession
node1 annotation
node2 annotation
score
ABF65025.1
ABF65027.1
TM1040_2293
TM1040_2295
annotation not available
annotation not available
0.459
ABF65025.1
carA
TM1040_2293
TM1040_2294
annotation not available
annotation not available
0.669
ABF65025.1
ribB
TM1040_2293
TM1040_2129
annotation not available
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family
0.855
ABF65027.1
ABF65025.1
TM1040_2295
TM1040_2293
annotation not available
annotation not available
0.459
ABF65027.1
carA
TM1040_2295
TM1040_2294
annotation not available
annotation not available
0.549
carA
ABF65025.1
TM1040_2294
TM1040_2293
annotation not available
annotation not available
0.669
carA
ABF65027.1
TM1040_2294
TM1040_2295
annotation not available
annotation not available
0.549
ribB
ABF65025.1
TM1040_2129
TM1040_2293
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family
annotation not available
0.855
Network Stats
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Functional enrichments in your networkNote: some enrichments may be expected here (why?) explain columns
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis, the following statistical background is assumed: