node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tbd_0537 | Tbd_0538 | Tbd_0537 | Tbd_0538 | Phosphatase kdsC. | Capsule expression protein KpsF/GutQ; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.995 |
Tbd_0537 | Tbd_2698 | Tbd_0537 | Tbd_2698 | Phosphatase kdsC. | Probable 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.561 |
Tbd_0537 | kdsA | Tbd_0537 | Tbd_0620 | Phosphatase kdsC. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.993 |
Tbd_0537 | kdsB | Tbd_0537 | Tbd_1505 | Phosphatase kdsC. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.997 |
Tbd_0537 | lpxA | Tbd_0537 | Tbd_0797 | Phosphatase kdsC. | Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.554 |
Tbd_0537 | lpxB | Tbd_0537 | Tbd_0798 | Phosphatase kdsC. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.498 |
Tbd_0537 | lpxD | Tbd_0537 | Tbd_0795 | Phosphatase kdsC. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase, LpxD; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.503 |
Tbd_0537 | lpxK | Tbd_0537 | Tbd_1508 | Phosphatase kdsC. | tetraacyldisaccharide-1-P 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.533 |
Tbd_0538 | Tbd_0537 | Tbd_0538 | Tbd_0537 | Capsule expression protein KpsF/GutQ; Belongs to the SIS family. GutQ/KpsF subfamily. | Phosphatase kdsC. | 0.995 |
Tbd_0538 | Tbd_2698 | Tbd_0538 | Tbd_2698 | Capsule expression protein KpsF/GutQ; Belongs to the SIS family. GutQ/KpsF subfamily. | Probable 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.845 |
Tbd_0538 | kdsA | Tbd_0538 | Tbd_0620 | Capsule expression protein KpsF/GutQ; Belongs to the SIS family. GutQ/KpsF subfamily. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.988 |
Tbd_0538 | kdsB | Tbd_0538 | Tbd_1505 | Capsule expression protein KpsF/GutQ; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.876 |
Tbd_0538 | lpxA | Tbd_0538 | Tbd_0797 | Capsule expression protein KpsF/GutQ; Belongs to the SIS family. GutQ/KpsF subfamily. | Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.748 |
Tbd_0538 | lpxB | Tbd_0538 | Tbd_0798 | Capsule expression protein KpsF/GutQ; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.786 |
Tbd_0538 | lpxD | Tbd_0538 | Tbd_0795 | Capsule expression protein KpsF/GutQ; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase, LpxD; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.759 |
Tbd_0538 | lpxK | Tbd_0538 | Tbd_1508 | Capsule expression protein KpsF/GutQ; Belongs to the SIS family. GutQ/KpsF subfamily. | tetraacyldisaccharide-1-P 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.847 |
Tbd_1506 | kdsB | Tbd_1506 | Tbd_1505 | tetraacyldisaccharide-1-P 4'-kinase; Belongs to the UPF0434 family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.871 |
Tbd_1506 | lpxK | Tbd_1506 | Tbd_1508 | tetraacyldisaccharide-1-P 4'-kinase; Belongs to the UPF0434 family. | tetraacyldisaccharide-1-P 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.718 |
Tbd_1565 | kdsB | Tbd_1565 | Tbd_1505 | Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.858 |
Tbd_2698 | Tbd_0537 | Tbd_2698 | Tbd_0537 | Probable 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Phosphatase kdsC. | 0.561 |