STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phnNGuanylate kinase/L-type calcium channel region; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (190 aa)    
Predicted Functional Partners:
Tbd_2290
Amidohydrolase-like protein.
  
 0.985
Tbd_2293
Phosphonate metabolism protein PhnJ; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family.
 
  
 0.978
Tbd_2294
Phosphonate metabolism protein.
 
  
 0.972
Tbd_2295
Putative PhnH protein, phosphonate metabolism, function unknown.
 
  
 0.971
Tbd_2291
ABC phosphonate transport system ATPase.
 
  
 0.970
Tbd_2292
ABC phosphonate transport system ATPase.
 
  
 0.961
Tbd_2288
Phosphonate metabolism protein, PhnP.
 
 
 0.939
Tbd_2296
Hypothetical protein.
  
  
 0.912
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
     
  0.900
Tbd_1465
Ribose-phosphate pyrophosphokinase.
     
  0.900
Your Current Organism:
Thiobacillus denitrificans ATCC 25259
NCBI taxonomy Id: 292415
Other names: T. denitrificans ATCC 25259, Thiobacillus denitrificans str. ATCC 25259, Thiobacillus denitrificans strain ATCC 25259
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.