node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Wbm0026 | Wbm0416 | Wbm0026 | Wbm0416 | Pyrimidine deaminase and reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | FAD synthase; Belongs to the ribF family. | 0.746 |
Wbm0026 | Wbm0699 | Wbm0026 | Wbm0699 | Pyrimidine deaminase and reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.614 |
Wbm0026 | coaD | Wbm0026 | Wbm0801 | Pyrimidine deaminase and reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.499 |
Wbm0026 | coaE | Wbm0026 | Wbm0259 | Pyrimidine deaminase and reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.581 |
Wbm0026 | guaA | Wbm0026 | Wbm0443 | Pyrimidine deaminase and reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.615 |
Wbm0026 | ispDF | Wbm0026 | Wbm0409 | Pyrimidine deaminase and reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.621 |
Wbm0416 | Wbm0026 | Wbm0416 | Wbm0026 | FAD synthase; Belongs to the ribF family. | Pyrimidine deaminase and reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.746 |
Wbm0416 | coaD | Wbm0416 | Wbm0801 | FAD synthase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.587 |
Wbm0416 | coaE | Wbm0416 | Wbm0259 | FAD synthase; Belongs to the ribF family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.487 |
Wbm0416 | ispDF | Wbm0416 | Wbm0409 | FAD synthase; Belongs to the ribF family. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.612 |
Wbm0699 | Wbm0026 | Wbm0699 | Wbm0026 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Pyrimidine deaminase and reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.614 |
Wbm0699 | Wbm0739 | Wbm0699 | Wbm0739 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.579 |
Wbm0699 | coaD | Wbm0699 | Wbm0801 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.597 |
Wbm0699 | guaA | Wbm0699 | Wbm0443 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.728 |
Wbm0699 | ispDF | Wbm0699 | Wbm0409 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.609 |
Wbm0739 | Wbm0699 | Wbm0739 | Wbm0699 | 3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.579 |
Wbm0739 | coaD | Wbm0739 | Wbm0801 | 3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.501 |
Wbm0739 | coaE | Wbm0739 | Wbm0259 | 3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.414 |
Wbm0791 | coaD | Wbm0791 | Wbm0801 | N6-adenine-specific methylase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.748 |
Wbm0800 | coaD | Wbm0800 | Wbm0801 | Protein containing predicted glutamine amidotransferase domain. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.489 |