Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
srrATranscriptional regulatory protein SrrA. (229 aa)    
Predicted Functional Partners:
OPJ56036.1
Blue-light-activated protein.
 
 0.977
phoR_2
Alkaline phosphatase synthesis sensor protein PhoR.
 
 0.975
kinE
Sporulation kinase E.
 
 
 0.914
yycG
Sensor histidine kinase YycG.
 0.897
phoR_1
Alkaline phosphatase synthesis sensor protein PhoR.
 0.884
hndC_1
NADP-reducing hydrogenase subunit HndC.
   
 
 0.800
hndC_2
NADP-reducing hydrogenase subunit HndC.
   
 
 0.800
hndA_1
NADP-reducing hydrogenase subunit HndA.
   
 
 0.777
sigA
RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.759
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.754
Your Current Organism:
Clostridium thermoalcaliphilum
NCBI taxonomy Id: 29349
Other names: ATCC 51508, CIP 105528, DSM 7309, [. thermoalcaliphilum, [Clostridium] thermoalcaliphilum, strain JW/YL23-2
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