STRINGSTRING
infC protein (Rickettsia canadensis) - STRING interaction network
"infC" - Translation initiation factor IF-3 in Rickettsia canadensis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
infCTranslation initiation factor IF-3; COG0625 Glutathione S-transferase (222 aa)    
Predicted Functional Partners:
rplR
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (118 aa)
     
      0.801
rpsB
COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family (295 aa)
     
        0.788
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family (172 aa)
     
   
  0.772
rplS
UPF0335 protein A1E_00570; COG3750 Uncharacterized protein conserved in bacteria; Belongs to the UPF0335 family (78 aa)
   
          0.764
A1E_05175
annotation not available (159 aa)
   
          0.733
A1E_01095
DNA helicase; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) (872 aa)
 
          0.713
efp
Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (188 aa)
   
 
  0.695
coaE
Dephospho-CoA kinase; COG3814 Uncharacterized protein conserved in bacteria (159 aa)
   
          0.677
A1E_02225
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination (241 aa)
 
     
  0.672
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (217 aa)
     
        0.598
Your Current Organism:
Rickettsia canadensis
NCBI taxonomy Id: 293613
Other names: R. canadensis str. McKiel, Rickettsia canadensis, Rickettsia canadensis str. McKiel, Rickettsia canadensis strain McKiel
Server load: low (10%) [HD]