node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A1E_00025 | A1E_01505 | A1E_00025 | A1E_01505 | Putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.512 |
A1E_00025 | A1E_01650 | A1E_00025 | A1E_01650 | Putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Acylglycerophosphoethanolamine acyltransferase. | 0.832 |
A1E_00025 | A1E_04785 | A1E_00025 | A1E_04785 | Putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Glutaredoxin-like protein grla; COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.528 |
A1E_00025 | lipA | A1E_00025 | A1E_04770 | Putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.510 |
A1E_01505 | A1E_00025 | A1E_01505 | A1E_00025 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.512 |
A1E_01505 | A1E_01650 | A1E_01505 | A1E_01650 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Acylglycerophosphoethanolamine acyltransferase. | 0.878 |
A1E_01505 | glyA-2 | A1E_01505 | A1E_04775 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.673 |
A1E_01505 | lipA | A1E_01505 | A1E_04770 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.718 |
A1E_01505 | lipB-2 | A1E_01505 | A1E_05610 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.707 |
A1E_01505 | polA | A1E_01505 | A1E_04970 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.574 |
A1E_01650 | A1E_00025 | A1E_01650 | A1E_00025 | Acylglycerophosphoethanolamine acyltransferase. | Putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.832 |
A1E_01650 | A1E_01505 | A1E_01650 | A1E_01505 | Acylglycerophosphoethanolamine acyltransferase. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.878 |
A1E_01650 | glyA-2 | A1E_01650 | A1E_04775 | Acylglycerophosphoethanolamine acyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.695 |
A1E_01650 | lipA | A1E_01650 | A1E_04770 | Acylglycerophosphoethanolamine acyltransferase. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.567 |
A1E_01650 | polA | A1E_01650 | A1E_04970 | Acylglycerophosphoethanolamine acyltransferase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.555 |
A1E_01650 | ybeY | A1E_01650 | A1E_04765 | Acylglycerophosphoethanolamine acyltransferase. | Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.872 |
A1E_02970 | lipA | A1E_02970 | A1E_04770 | Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.651 |
A1E_02970 | polA | A1E_02970 | A1E_04970 | Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.841 |
A1E_04785 | A1E_00025 | A1E_04785 | A1E_00025 | Glutaredoxin-like protein grla; COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.528 |
A1E_04785 | lipA | A1E_04785 | A1E_04770 | Glutaredoxin-like protein grla; COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.507 |