STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eraGTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (293 aa)    
Predicted Functional Partners:
rpsP
COG0228 Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
   
 0.991
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
    
 0.989
rpsF-2
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
  0.988
rpsI
COG0103 Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
 0.987
rpsJ
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 0.982
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
 0.981
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
    
 0.979
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
  
 0.978
rpsN
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
   
 0.978
rpsB
COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
  0.975
Your Current Organism:
Rickettsia akari
NCBI taxonomy Id: 293614
Other names: R. akari str. Hartford, Rickettsia akari str. Hartford, Rickettsia akari strain Hartford
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.