STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (424 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.999
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: chy:CHY_1212 glutamate-1-semialdehyde-2,1-aminomutase.
 
 0.998
Amet_0061
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein.
 
  
 0.989
Amet_0062
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mta:Moth_1246 porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.971
Amet_0059
TIGRFAM: siroheme synthase; KEGG: gka:GK0404 siroheme synthase.
 
   
 0.921
Amet_0074
TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: fnu:FN0957 precorrin-4 C11-methyltransferase.
 
   
 0.635
Amet_0064
PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: ppd:Ppro_1299 cobalamin (vitamin B12) biosynthesis CbiX protein.
 
  
 0.609
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
     
 0.604
Amet_2918
PFAM: cytochrome c assembly protein; KEGG: mta:Moth_2200 cytochrome c assembly protein.
 
  
 0.600
Amet_0073
TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mta:Moth_1091 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
     
 0.568
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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