node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Amet_0059 | Amet_0061 | Amet_0059 | Amet_0061 | TIGRFAM: siroheme synthase; KEGG: gka:GK0404 siroheme synthase. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein. | 0.999 |
Amet_0059 | Amet_0062 | Amet_0059 | Amet_0062 | TIGRFAM: siroheme synthase; KEGG: gka:GK0404 siroheme synthase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mta:Moth_1246 porphobilinogen synthase; Belongs to the ALAD family. | 0.918 |
Amet_0059 | Amet_0064 | Amet_0059 | Amet_0064 | TIGRFAM: siroheme synthase; KEGG: gka:GK0404 siroheme synthase. | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: ppd:Ppro_1299 cobalamin (vitamin B12) biosynthesis CbiX protein. | 0.982 |
Amet_0059 | Amet_0073 | Amet_0059 | Amet_0073 | TIGRFAM: siroheme synthase; KEGG: gka:GK0404 siroheme synthase. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mta:Moth_1091 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.944 |
Amet_0059 | Amet_0074 | Amet_0059 | Amet_0074 | TIGRFAM: siroheme synthase; KEGG: gka:GK0404 siroheme synthase. | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: fnu:FN0957 precorrin-4 C11-methyltransferase. | 0.969 |
Amet_0059 | cbiA | Amet_0059 | Amet_0065 | TIGRFAM: siroheme synthase; KEGG: gka:GK0404 siroheme synthase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.520 |
Amet_0059 | hemA | Amet_0059 | Amet_0058 | TIGRFAM: siroheme synthase; KEGG: gka:GK0404 siroheme synthase. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.921 |
Amet_0059 | hemC | Amet_0059 | Amet_0060 | TIGRFAM: siroheme synthase; KEGG: gka:GK0404 siroheme synthase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.993 |
Amet_0059 | hemL | Amet_0059 | Amet_0063 | TIGRFAM: siroheme synthase; KEGG: gka:GK0404 siroheme synthase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: chy:CHY_1212 glutamate-1-semialdehyde-2,1-aminomutase. | 0.976 |
Amet_0061 | Amet_0059 | Amet_0061 | Amet_0059 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein. | TIGRFAM: siroheme synthase; KEGG: gka:GK0404 siroheme synthase. | 0.999 |
Amet_0061 | Amet_0062 | Amet_0061 | Amet_0062 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mta:Moth_1246 porphobilinogen synthase; Belongs to the ALAD family. | 0.999 |
Amet_0061 | Amet_0064 | Amet_0061 | Amet_0064 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein. | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: ppd:Ppro_1299 cobalamin (vitamin B12) biosynthesis CbiX protein. | 0.860 |
Amet_0061 | Amet_0073 | Amet_0061 | Amet_0073 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mta:Moth_1091 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.968 |
Amet_0061 | Amet_0074 | Amet_0061 | Amet_0074 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein. | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: fnu:FN0957 precorrin-4 C11-methyltransferase. | 0.764 |
Amet_0061 | Amet_2918 | Amet_0061 | Amet_2918 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein. | PFAM: cytochrome c assembly protein; KEGG: mta:Moth_2200 cytochrome c assembly protein. | 0.954 |
Amet_0061 | cbiA | Amet_0061 | Amet_0065 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.882 |
Amet_0061 | hemA | Amet_0061 | Amet_0058 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.989 |
Amet_0061 | hemC | Amet_0061 | Amet_0060 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
Amet_0061 | hemL | Amet_0061 | Amet_0063 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: chy:CHY_1212 glutamate-1-semialdehyde-2,1-aminomutase. | 0.985 |
Amet_0062 | Amet_0059 | Amet_0062 | Amet_0059 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mta:Moth_1246 porphobilinogen synthase; Belongs to the ALAD family. | TIGRFAM: siroheme synthase; KEGG: gka:GK0404 siroheme synthase. | 0.918 |