node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Amet_0169 | Amet_0173 | Amet_0169 | Amet_0173 | PFAM: YabP family protein; KEGG: tte:TTE2450 hypothetical protein. | Sporulation stage II, protein E; KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: Sporulation stage II, protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. | 0.842 |
Amet_0169 | Amet_0364 | Amet_0169 | Amet_0364 | PFAM: YabP family protein; KEGG: tte:TTE2450 hypothetical protein. | TIGRFAM: Sporulation stage III, transcriptional regulator SpoIIID; KEGG: cno:NT01CX_0524 stage III sporulation protein D. | 0.796 |
Amet_0169 | Amet_2492 | Amet_0169 | Amet_2492 | PFAM: YabP family protein; KEGG: tte:TTE2450 hypothetical protein. | TIGRFAM: Sporulation stage III, protein AA; SMART: AAA ATPase; KEGG: cth:Cthe_0845 stage III sporulation protein spoIIIAA. | 0.810 |
Amet_0169 | Amet_2513 | Amet_0169 | Amet_2513 | PFAM: YabP family protein; KEGG: tte:TTE2450 hypothetical protein. | Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.536 |
Amet_0169 | Amet_2854 | Amet_0169 | Amet_2854 | PFAM: YabP family protein; KEGG: tte:TTE2450 hypothetical protein. | Sporulation stage IV, protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.774 |
Amet_0169 | Amet_2870 | Amet_0169 | Amet_2870 | PFAM: YabP family protein; KEGG: tte:TTE2450 hypothetical protein. | RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.725 |
Amet_0169 | Amet_2872 | Amet_0169 | Amet_2872 | PFAM: YabP family protein; KEGG: tte:TTE2450 hypothetical protein. | Peptidase U4, sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.805 |
Amet_0169 | Amet_3054 | Amet_0169 | Amet_3054 | PFAM: YabP family protein; KEGG: tte:TTE2450 hypothetical protein. | PFAM: Stage II sporulation P family protein; KEGG: tte:TTE0947 stage II sporulation protein P. | 0.759 |
Amet_0169 | Amet_4592 | Amet_0169 | Amet_4592 | PFAM: YabP family protein; KEGG: tte:TTE2450 hypothetical protein. | TIGRFAM: Sporulation stage II, protein R; KEGG: cth:Cthe_1920 stage II sporulation protein R. | 0.816 |
Amet_0169 | spoIIAB | Amet_0169 | Amet_2213 | PFAM: YabP family protein; KEGG: tte:TTE2450 hypothetical protein. | Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.777 |
Amet_0173 | Amet_0169 | Amet_0173 | Amet_0169 | Sporulation stage II, protein E; KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: Sporulation stage II, protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. | PFAM: YabP family protein; KEGG: tte:TTE2450 hypothetical protein. | 0.842 |
Amet_0173 | Amet_0364 | Amet_0173 | Amet_0364 | Sporulation stage II, protein E; KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: Sporulation stage II, protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. | TIGRFAM: Sporulation stage III, transcriptional regulator SpoIIID; KEGG: cno:NT01CX_0524 stage III sporulation protein D. | 0.869 |
Amet_0173 | Amet_2492 | Amet_0173 | Amet_2492 | Sporulation stage II, protein E; KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: Sporulation stage II, protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. | TIGRFAM: Sporulation stage III, protein AA; SMART: AAA ATPase; KEGG: cth:Cthe_0845 stage III sporulation protein spoIIIAA. | 0.851 |
Amet_0173 | Amet_2513 | Amet_0173 | Amet_2513 | Sporulation stage II, protein E; KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: Sporulation stage II, protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. | Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.883 |
Amet_0173 | Amet_2854 | Amet_0173 | Amet_2854 | Sporulation stage II, protein E; KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: Sporulation stage II, protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. | Sporulation stage IV, protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.838 |
Amet_0173 | Amet_2870 | Amet_0173 | Amet_2870 | Sporulation stage II, protein E; KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: Sporulation stage II, protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. | RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.870 |
Amet_0173 | Amet_2872 | Amet_0173 | Amet_2872 | Sporulation stage II, protein E; KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: Sporulation stage II, protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. | Peptidase U4, sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.962 |
Amet_0173 | Amet_3054 | Amet_0173 | Amet_3054 | Sporulation stage II, protein E; KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: Sporulation stage II, protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. | PFAM: Stage II sporulation P family protein; KEGG: tte:TTE0947 stage II sporulation protein P. | 0.905 |
Amet_0173 | Amet_4592 | Amet_0173 | Amet_4592 | Sporulation stage II, protein E; KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: Sporulation stage II, protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. | TIGRFAM: Sporulation stage II, protein R; KEGG: cth:Cthe_1920 stage II sporulation protein R. | 0.907 |
Amet_0173 | spoIIAB | Amet_0173 | Amet_2213 | Sporulation stage II, protein E; KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: Sporulation stage II, protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. | Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.906 |