STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amet_3021PFAM: CBS domain containing protein; Helix-turn-helix, type 11 domain protein; KEGG: ctc:CTC02015 conserved protein with cbs domain. (212 aa)    
Predicted Functional Partners:
Amet_3020
Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
 
  
 0.963
Amet_3019
TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising protein, mobile region; KEGG: tte:TTE0981 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
 
    0.801
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.549
glyQS
glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.508
Amet_2991
PFAM: protein of unknown function DUF633; KEGG: tte:TTE1754 predicted SAM-dependent methyltransferase.
 
     0.456
rnmV
Primase/topoisomerase like protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
  
     0.436
Amet_2529
Polynucleotide adenylyltransferase region; PFAM: CBS domain containing protein; phosphoesterase, RecJ domain protein; Polynucleotide adenylyltransferase region; KEGG: cth:Cthe_0684 polynucleotide adenylyltransferase region; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
     
 0.421
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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