STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (318 aa)    
Predicted Functional Partners:
birA
biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.964
Amet_4104
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: tte:TTE1073 Biotin synthase and related enzymes.
  
  
 
0.911
Amet_0697
TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: cac:CAC1427 4-aminobutyrate aminotransferase (PLP-dependent); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
    
 0.892
argD
TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: mta:Moth_2287 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
  
 0.880
Amet_3634
Pyridoxal phosphate-dependent acyltransferase, putative; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
  
 0.857
Amet_3240
PFAM: BioY protein; KEGG: cac:CAC3456 uncharacterized conserved protein, bioY family.
  
  
 0.832
Amet_4317
PFAM: aminotransferase class-III; KEGG: tte:TTE2339 PLP-dependent aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
  
 0.739
Amet_3096
Molybdopterin oxidoreductase; PFAM: ferredoxin; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; KEGG: swo:Swol_0658 glutamate synthase beta chain-related oxidoreductase, containing 2Fe-2S and 4Fe-4S clusters.
     
 0.627
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.586
Amet_3193
PFAM: aminotransferase class-III; KEGG: bcl:ABC2432 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
  
 0.570
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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