node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Amet_2885 | Amet_3426 | Amet_2885 | Amet_3426 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein; KEGG: tte:TTE1651 Cell division protein FtsI/penicillin-binding protein 2. | PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; KEGG: cth:Cthe_0977 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase. | 0.858 |
Amet_2885 | Amet_4145 | Amet_2885 | Amet_4145 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein; KEGG: tte:TTE1651 Cell division protein FtsI/penicillin-binding protein 2. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.588 |
Amet_2885 | ddl | Amet_2885 | Amet_3710 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein; KEGG: tte:TTE1651 Cell division protein FtsI/penicillin-binding protein 2. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.601 |
Amet_2885 | mraY | Amet_2885 | Amet_2882 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein; KEGG: tte:TTE1651 Cell division protein FtsI/penicillin-binding protein 2. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.967 |
Amet_2885 | murB | Amet_2885 | Amet_4093 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein; KEGG: tte:TTE1651 Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.714 |
Amet_2885 | murC | Amet_2885 | Amet_0153 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein; KEGG: tte:TTE1651 Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.906 |
Amet_2885 | murD | Amet_2885 | Amet_2881 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein; KEGG: tte:TTE1651 Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.936 |
Amet_2885 | murF | Amet_2885 | Amet_2883 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein; KEGG: tte:TTE1651 Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.923 |
Amet_2885 | murF-2 | Amet_2885 | Amet_3709 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein; KEGG: tte:TTE1651 Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.806 |
Amet_2885 | murG | Amet_2885 | Amet_2879 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein; KEGG: tte:TTE1651 Cell division protein FtsI/penicillin-binding protein 2. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.902 |
Amet_3426 | Amet_2885 | Amet_3426 | Amet_2885 | PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; KEGG: cth:Cthe_0977 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein; KEGG: tte:TTE1651 Cell division protein FtsI/penicillin-binding protein 2. | 0.858 |
Amet_3426 | Amet_4145 | Amet_3426 | Amet_4145 | PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; KEGG: cth:Cthe_0977 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.801 |
Amet_3426 | ddl | Amet_3426 | Amet_3710 | PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; KEGG: cth:Cthe_0977 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.973 |
Amet_3426 | mraY | Amet_3426 | Amet_2882 | PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; KEGG: cth:Cthe_0977 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.991 |
Amet_3426 | murB | Amet_3426 | Amet_4093 | PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; KEGG: cth:Cthe_0977 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.745 |
Amet_3426 | murC | Amet_3426 | Amet_0153 | PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; KEGG: cth:Cthe_0977 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.790 |
Amet_3426 | murD | Amet_3426 | Amet_2881 | PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; KEGG: cth:Cthe_0977 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.926 |
Amet_3426 | murF | Amet_3426 | Amet_2883 | PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; KEGG: cth:Cthe_0977 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.921 |
Amet_3426 | murF-2 | Amet_3426 | Amet_3709 | PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; KEGG: cth:Cthe_0977 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.926 |
Amet_3426 | murG | Amet_3426 | Amet_2879 | PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein; KEGG: cth:Cthe_0977 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.946 |