STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hisC-2TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: mta:Moth_0515 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (358 aa)    
Predicted Functional Partners:
hisI
PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: tte:TTE2132 phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family.
 
  
 0.999
hisB
PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: cth:Cthe_2884 imidazoleglycerol-phosphate dehydratase.
 
 0.998
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 0.978
Amet_0646
Prephenate dehydrogenase; PFAM: amino acid-binding ACT domain protein; Prephenate dehydrogenase; NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mta:Moth_1333 prephenate dehydrogenase.
 
 
 0.977
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; Allinase-like; KEGG: cno:NT01CX_1063 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 
0.919
pheA
PFAM: prephenate dehydratase; KEGG: mtp:Mthe_0937 prephenate dehydratase.
  
 
 0.919
Amet_3162
TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP C-terminal domain protein; KEGG: oih:OB0554 histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.
  
 
 0.909
Amet_3545
TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: dsy:DSY1025 hypothetical protein; Belongs to the PHP hydrolase family. HisK subfamily.
  
 
 0.909
katG1
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
 0.902
katG2
Catalase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
 0.902
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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