STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiCUnannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (434 aa)    
Predicted Functional Partners:
GCA_002005185_00890
Unannotated protein.
 
 
 0.982
thiG
Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.976
thiM
Unannotated protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the thiamine-phosphate synthase family.
 
  
 0.973
GCA_002005185_01094
Unannotated protein.
 
  
 0.955
GCA_002005185_01092
Unannotated protein.
  
  
 0.898
thiE
Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.884
purM
Unannotated protein.
     
 0.802
GCA_002005185_01095
Unannotated protein.
       0.695
GCA_002005185_01864
Unannotated protein.
 
  
 0.615
GCA_002005185_01090
Unannotated protein; Belongs to the ClpA/ClpB family.
       0.417
Your Current Organism:
Veillonella parvula
NCBI taxonomy Id: 29466
Other names: ATCC 10790, ATCC 17745 [[Veillonella alcalescens]], CCUG 5123, DSM 2008, JCM 12972, Micrococcus gazogenes, Micrococcus gazogenes alcalescens anaerobius, Micrococcus lactilyticus, NCTC 11810, Staphylococcus parvulus, V. parvula, Veillonella alcalescens, Veillonella gazogenes
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