node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CTRG_00165 | CTRG_00642 | C5M276 | C5M3K3 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.574 |
CTRG_00165 | CTRG_03051 | C5M276 | C5MAF9 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.578 |
CTRG_00165 | CTRG_03198 | C5M276 | C5MAV6 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | Putative_PNPOx domain-containing protein. | 0.770 |
CTRG_00165 | CTRG_03500 | C5M276 | C5MBQ8 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | Anthranilate synthase component II. | 0.594 |
CTRG_00165 | CTRG_03628 | C5M276 | C5MC36 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.990 |
CTRG_00165 | CTRG_03655 | C5M276 | C5MC63 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | Uncharacterized protein; Belongs to the BolA/IbaG family. | 0.565 |
CTRG_00165 | CTRG_04781 | C5M276 | C5MFD8 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.981 |
CTRG_00165 | CTRG_04923 | C5M276 | C5MFT0 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | Cysteine desulfurase, mitochondrial. | 0.565 |
CTRG_00165 | CTRG_05389 | C5M276 | C5MH35 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | BPL/LPL catalytic domain-containing protein. | 0.986 |
CTRG_00165 | CTRG_06075 | C5M276 | C5MJ32 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | GTP cyclohydrolase I. | 0.570 |
CTRG_00642 | CTRG_00165 | C5M3K3 | C5M276 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | 0.574 |
CTRG_00642 | CTRG_03051 | C5M3K3 | C5MAF9 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.620 |
CTRG_00642 | CTRG_03500 | C5M3K3 | C5MBQ8 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Anthranilate synthase component II. | 0.586 |
CTRG_00642 | CTRG_04923 | C5M3K3 | C5MFT0 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Cysteine desulfurase, mitochondrial. | 0.546 |
CTRG_03051 | CTRG_00165 | C5MAF9 | C5M276 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | 0.578 |
CTRG_03051 | CTRG_00642 | C5MAF9 | C5M3K3 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.620 |
CTRG_03051 | CTRG_03500 | C5MAF9 | C5MBQ8 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Anthranilate synthase component II. | 0.586 |
CTRG_03051 | CTRG_04923 | C5MAF9 | C5MFT0 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Cysteine desulfurase, mitochondrial. | 0.550 |
CTRG_03198 | CTRG_00165 | C5MAV6 | C5M276 | Putative_PNPOx domain-containing protein. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. | 0.770 |
CTRG_03198 | CTRG_03628 | C5MAV6 | C5MC36 | Putative_PNPOx domain-containing protein. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.788 |