STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZOSMA_33G00380AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (167 aa)    
Predicted Functional Partners:
A0A0K9PEM5
AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which seems to be clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole. It also function in maintaining the identity of lytic vacuoles and in regulating the transition between storage and lytic vacuoles.
    
 0.983
ZOSMA_88G00230
AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.
    
 0.981
ZOSMA_92G00400
AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family.
   
 0.976
ZOSMA_42G00430
AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.
    
 0.863
ZOSMA_31G00660
AP-1 complex subunit gamma.
    
 0.863
ZOSMA_2G02420
AP-2 complex subunit alpha; Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome.
    
 0.797
A0A0K9PFU8
Putative AP-2 complex subunit alpha.
    
 0.797
ZOSMA_24G01200
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
    
 0.797
A0A0K9PUA1
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
    
 0.797
ZOSMA_15G00480
Adaptin_N domain-containing protein.
    
 0.797
Your Current Organism:
Zostera marina
NCBI taxonomy Id: 29655
Other names: Z. marina, Zostera marina L.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.