STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: fal:FRAAL0997 glutamate-1-semialdehyde aminotransferase (aminomutase), PLP-dependent. (449 aa)    
Predicted Functional Partners:
ABW15472.1
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: fal:FRAAL0986 5-aminolevulinate dehydratase (porphobilinogen synthase); Belongs to the ALAD family.
 
 
 0.993
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.991
ABW15466.1
PFAM: Phosphoglycerate mutase; KEGG: fal:FRAAL0998 probable phosphoglycerate mutase (phosphoglyceromutase) (PgaM).
  
    0.935
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.922
ABW10405.1
PFAM: aminotransferase class-III; KEGG: fal:FRAAL6024 putative glutamate-1-semialdehyde aminotransferase (aminomutase), PLP-dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.918
ABW15446.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: fal:FRAAL1020 uroporphyrin-III C-methyltransferase.
 
  
 0.821
ABW15473.1
Uroporphyrinogen III synthase HEM4; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: fal:FRAAL0985 uroporphyrin-III C-methyltransferase.
 
  
 0.811
ABW13546.1
TIGRFAM: precorrin-4 C11-methyltransferase; precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: sco:SCO1857 putative bifunctional protein (CbiGH).
 
   
 0.799
ABW15464.1
Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Thioredoxin domain; KEGG: fal:FRAAL1001 thiol:disulfide interchange protein HelX precursor (cytochrome c biogenesis protein HelX).
  
  
 0.795
ABW15463.1
PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: fal:FRAAL1002 putative cytochrome c biogenesis membrane protein.
  
  
 0.775
Your Current Organism:
Frankia sp. EAN1pec
NCBI taxonomy Id: 298653
Other names: F. sp. EAN1pec
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.