STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (968 aa)    
Predicted Functional Partners:
ADP84757.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.976
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.961
ADP82823.1
PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; manually curated; KEGG: fal:FRAAL4537 pyruvate kinase; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.950
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.940
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 
 0.937
ADP81043.1
PFAM: Citrate synthase; regulatory protein MerR; KEGG: sgr:SGR_1692 putative citrate synthase-like protein.
 
  
 0.907
ADP85058.1
TIGRFAM: citrate synthase I; KEGG: fal:FRAAL0111 citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
    
 0.895
ADP81042.1
KEGG: sgr:SGR_1691 putative citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
  
 0.880
ADP85060.1
KEGG: fal:FRAAL0109 citrate synthase 2; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
  
 0.874
ADP80025.1
TIGRFAM: malate synthase A; KEGG: sth:STH589 malate synthase; PFAM: Malate synthase family protein; Belongs to the malate synthase family.
     
 0.844
Your Current Organism:
Frankia inefficax
NCBI taxonomy Id: 298654
Other names: CECT 9037, DSM 45817, F. inefficax, Frankia inefficax Nouioui et al. 2017, Frankia sp. EuI1c, strain EuI1c
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