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CTU1 protein (Hypocrea virens) - STRING interaction network
"CTU1" - Hypothetical protein in Hypocrea virens
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second shell of interactors
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proteins of unknown 3D structure
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Predicted Interactions
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textmining
co-expression
protein homology
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CTU1Hypothetical protein; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation (392 aa)    
Predicted Functional Partners:
CTU2
Hypothetical protein; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation (377 aa)
     
  0.984
EHK25540
Hypothetical protein (542 aa)
       
  0.828
EHK22368
Hypothetical protein (534 aa)
       
  0.828
URM1
Hypothetical protein; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2- thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target protein [...] (112 aa)
       
  0.669
EHK25514
Hypothetical protein (547 aa)
   
 
  0.640
EHK24451
Hypothetical protein (1184 aa)
 
            0.637
EHK19598
Hypothetical protein (567 aa)
     
 
  0.625
EHK17749
Hypothetical protein; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis (1569 aa)
     
 
  0.621
EHK20317
Hypothetical protein (1861 aa)
   
   
  0.617
CNXF
Hypothetical protein; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the p [...] (462 aa)
     
 
  0.539
Your Current Organism:
Hypocrea virens
NCBI taxonomy Id: 29875
Other names: Gliocladium flavofuscum, Gliocladium virens, H. virens, Hypocrea virens, Trichoderma flavofuscum, Trichoderma virens
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