STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL18Interleukin-18. (188 aa)    
Predicted Functional Partners:
IL18R1
Interleukin-18 receptor 1.
   
 0.997
IL18RAP
Interleukin-18 receptor accessory protein.
  
 0.974
NFKB1
Nuclear factor NF-kappa-B p105 subunit.
     
 0.920
JUN
Transcription factor AP-1.
     
 0.911
IL6
Interleukin-6.
     
 0.816
IL10
Interleukin-10.
   
 
 0.815
IL22
Interleukin-22.
  
   
 0.753
IL1B
Interleukin-1; Belongs to the IL-1 family.
   
 0.709
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
  
  
 0.695
IL15
Interleukin; Belongs to the IL-15/IL-21 family.
      
 0.671
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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