STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yaeEPutative transport system permease protein; Code: P; COG: COG2011. (217 aa)    
Predicted Functional Partners:
yaeC
Putative lipoprotein; Code: P; COG: COG1464; Belongs to the nlpA lipoprotein family.
 0.999
abc
ATP-binding component of a transporter; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 0.999
nlpA
Lipoprotein-28; Code: P; COG: COG1464; Belongs to the nlpA lipoprotein family.
 0.999
metA
Homoserine transsuccinylase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
  
  
 0.619
yaeD
Putative phosphatase; Code: E; COG: COG0241.
       0.561
metF
5,10-methylenetetrahydrofolate reductase; Code: E; COG: COG0685; Belongs to the methylenetetrahydrofolate reductase family.
   
    0.467
yaeB
Conserved hypothetical protein; Code: S; COG: COG1720; orf.
       0.440
rcsF
Regulator in colanic acid synthesis; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
       0.434
metR
Regulator for metE and metH; Code: K; COG: COG0583; Belongs to the LysR transcriptional regulatory family.
   
    0.405
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.