STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsxNucleoside channel; Receptor of phage T6 and colicin K; Code: M; COG: COG3248. (294 aa)    
Predicted Functional Partners:
btuB
Outer membrane receptor for transport of vitamin B12, E colicins, and bacteriophage BF23; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
     
 0.808
ompA
Outer membrane protein 3a; II*;G;d; Code: M; COG: COG2885; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
     
 0.797
ompF
Outer membrane protein 1a (Ia;b;F); Code: M; COG: COG3203; Belongs to the Gram-negative porin family.
  
 
 0.793
ompC
Outer membrane protein 1b; Ib;c; Code: M; COG: COG3203; Belongs to the Gram-negative porin family.
  
 
 0.792
fepA
Outer membrane receptor for ferric enterobactin (enterochelin) and colicins B and D; Code: P; COG: COG4771.
  
   
 0.733
yhcP
Conserved hypothetical protein; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
  
     0.720
yccZ
Putative function in exopolysaccharide production; Code: M; COG: COG1596.
  
  
  0.719
ytfN
Conserved hypothetical protein; Code: S; COG: COG2911; orf.
  
     0.699
ycfM
Conserved hypothetical protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family.
  
   
 0.616
yigJ
Conserved hypothetical protein; Code: E; COG: COG1280; orf.
  
     0.587
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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