STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsuA16S pseudouridylate 516 synthase; Code: J; COG: COG1187; Belongs to the pseudouridine synthase RsuA family. (231 aa)    
Predicted Functional Partners:
bcr
Bicyclomycin resistance protein; Transmembrane protein; Code: GEPR; COG: COG0477.
      0.691
der
Putative GTP-binding factor; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.670
yejH
Putative ATP-dependent helicase; Code: KL; COG: COG1061.
       0.549
yfiF
Conserved hypothetical protein; Code: J; COG: COG0566; orf; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
 
 0.534
xthA
Exonuclease III; Code: L; COG: COG0708.
  
    0.530
cmk
Cytidylate kinase; Code: F; COG: COG0283.
  
  
 0.510
ycbY
Putative oxidoreductase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
 
 
 0.495
phoQ
Sensor protein PhoQ; Code: T; COG: COG0642.
 
     0.479
truB
tRNA pseudouridine 5S synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
   
 0.457
helD
DNA helicase IV; Code: L; COG: COG0210.
 
     0.432
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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