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aceK protein (Pseudomonas oleovorans) - STRING interaction network
"aceK" - Isocitrate dehydrogenase kinase/phosphatase in Pseudomonas oleovorans
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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aceKIsocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (574 aa)    
Predicted Functional Partners:
JNHE01000033_gene969
annotation not available (422 aa)
 
 
 
  0.947
JNHE01000033_gene958
annotation not available (499 aa)
   
   
  0.912
JNHE01000006_gene1029
annotation not available (1441 aa)
       
  0.893
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family (953 aa)
   
   
    0.807
JNHE01000006_gene1028
annotation not available (472 aa)
       
    0.759
JNHE01000012_gene1397
annotation not available (943 aa)
       
  0.759
JNHE01000016_gene4550
annotation not available (849 aa)
         
  0.739
JNHE01000018_gene3864
annotation not available (296 aa)
 
          0.731
JNHE01000012_gene1399
annotation not available (478 aa)
         
  0.700
JNHE01000049_gene1500
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily (390 aa)
   
   
  0.658
Your Current Organism:
Pseudomonas oleovorans
NCBI taxonomy Id: 301
Other names: ATCC 8062, CCUG 2087, CFBP 5589, CIP 59.11, IFO 13583, JCM 11598, LMG 2229, NBRC 13583, NCIMB 6576, NCTC 10692, NRRL B-778, P. oleovorans, Pseudomonas oleovorans, Pseudomonas sp. MGY01
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